Deerfield Management Companies

Senior Research Associate/Scientist: Antibody Discovery

Job Locations US-CA-San Diego
Job Post Information* : Posted Date 1 month ago(8/19/2021 12:38 PM)
# of Openings
Research & Development


AlivaMab Discovery Services, LLC (ADS) is recruiting for an outstanding individual with a range of skill sets supporting the successful discovery of fully human antibody drug candidates from the AlivaMab® Mouse platform.  This candidate should be a motivated team player, able to wear multiple hats while working in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs.


Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services continues expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients.



Your primary responsibilities will be in the area of animal immunizations, hybridoma generation, tissue culture, and antibody screening by ELISA, FACS, and functional assays.  You will be executing and delivering for projects and preparing written reports.  We are looking for independent and creative researchers that demonstrate initiative, who are capable of experimental design and execution, including troubleshooting.  You will work closely with other team members and leaders.  You will be able to effectively present and communicate concepts and results, both orally and in writing, to management and clients.






Key Skills and Requirements:

  • B.S., M.S., or PhD degree in life sciences or related discipline with three or more years' directly relevant experience
  • Impeccable cell culture and sterile technique is essential for success in this role
  • Ability to efficiently work in team-based environment on challenging drug discovery projects requiring high throughput cell culture and screening
  • Experience in multiple antibody screening assay methods (ELISA, FACS, Octet, functional assays)
  • Experience performing cell-based functional assays to identify functional antibody candidates. Functional assay development/optimization experience a plus
  • Prior experience in small animal immunizations with recombinant proteins, cells and DNA (HDTVI experience strongly desired) for the discovery of therapeutic antibody drug candidates
  • Excellent organization in day to day experiments and timely updating of experiment files
  • Proficiency in Microsoft Office Suite (Word, Excel and PowerPoint) and Graphpad Prism
  • Nice to have: previous experience in stable cell line generation, hybridoma fusions, FACS sorting, protein purification/characterization and general molecular biology skills


AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.





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