Deerfield Management Companies

Scientist/ Senior Scientist, Antibody Engineering, Molecular Biology, and Phage Display

Job Locations US-CA-San Diego
Job Post Information* : Posted Date 1 month ago(12/10/2021 3:28 PM)
ID
2021-1658
# of Openings
1
Category
Research & Development

Overview

Scientist / Sr. Scientist Antibody Engineering, Molecular Biology, and Phage Display

Overview

AlivaMab Discovery Services is seeking an outstanding individual with a wide range of skills in antibody bacteriophage display, molecular biology and purification technologies to join our collaborative and innovative therapeutic antibody engineering team. Title will be commensurate with experience.

AlivaMab Discovery Services is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab® Mouse suite of transgenic mice. We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics and developability, with expanding capabilities for engineering for alternative formats, including multispecifics and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.

Responsibilities

 

  • Conduct antibody phage display, molecular biology and analytical data generation and analysis.
  • Design and optimize molecular biology workflows for speed and efficiency.
  • Design and construct antibody phage display libraries.
  • Build and work with state-of-the-art engineered antibodies and multispecifics

Design and tune antibody phage display platform technologies.

  • Execute projects and prepare written reports.
  • Experimental design, experiment execution and troubleshooting.
  • Work closely with other team members and leaders.
  • Effectively present and communicate concepts and results, both orally and in writing, to colleagues and management.

Qualifications

 

Key Skills and Requirements:

 

  • MS with a minimum of 5 years of related experience or PhD with a minimum of 2 years of related experience.
  • Strong knowledge and skills in antibody bacteriophage display and library design/construction.
  • Strong knowledge and skills in molecular biology and construct design.
  • Experience with molecular biology techniques (PCR, DNA/RNA isolation, plasmid prep, gel extraction, cloning, Gibson assembly, Sanger sequence analysis, NGS sequence analysis).
  • Excellent troubleshooting and problem-solving capabilities.
  • Extraordinary attention to detail, planning skills and organizational skills.
  • History of timeline-driven delivery.
  • Outstanding oral and written communication skills.
  • Independent and creative researcher who demonstrate initiative.
  • Proficiency with Microsoft Office and sequence analysis software.
  • Experience with any of the following is a plus: protein expression in CHO, bacteria, yeast or insect cell systems, antibody engineering and reformatting, high-throughput recombinant expression.

About AlivaMab Discovery Services

AlivaMab Discovery Services (ADS) sets its partners’ antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, ADS delivers drug-quality, fully human antibodies on exceptional timelines. ADS achieves its partners’ design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. ADS focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multispecifics and CARs. The ADS team’s experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab® Mouse platforms, ensure the highest probability of success.

 

AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

 

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