Deerfield Management Companies

Research Associate, Antibody Discovery

Job Locations US-CA-San Diego
Job Post Information* : Posted Date 1 month ago(5/18/2022 2:07 PM)
ID
2022-1769
# of Openings
1
Category
Research & Development

Overview

AlivaMab Discovery Services is seeking an outstanding individual with a broad range of skills to support the successful discovery of fully human antibody drug candidates from the AlivaMab® Mouse platform. The successful candidate will be a highly motivated team player and able to multitask in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs.

 

AlivaMab Discovery Services is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab® Mouse suite of transgenic mice. We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics and developability, with expanding capabilities for engineering for alternative formats, including multispecifics and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.

Responsibilities

  •  Maintenance of mammalian cell lines for cell-based assays for multiple projects.
  • Antibody screening utilizing ELISA, flow cytometry and cell-based functional assays.
  • Reagent preparation and keeping inventory up to date.
  • Take on the role of an independent and creative researcher who demonstrates initiative in experimental design and execution, including troubleshooting.
  • Work closely with other team members and leaders supporting multiple drug discovery projects.
  • Effectively present and communicate concepts and results, both orally and in writing, to the team.

Qualifications

Key Skills and Requirements:

  • BS or MS in Immunology, cell biology or related discipline with 0-3 years of relevant industrial or academic experience.
  • Aseptic tissue culture experience is a requirement for the position (in either industry or academic settings.) Demonstrated technical expertise in mammalian tissue culture of cancer cell lines and hybridomas is preferred.  
  • Handling small animals including immunization, blood drawing and harvesting tissue is highly desired.
  • Ability to efficiently work both independently and in a team-based environment on challenging drug discovery projects utilizing high-throughput cell culture and antibody screening techniques.
  • The right candidate for excelling in this position will be self-motivated, display strong attention to detail and have a desire to learn and develop new skills and techniques for antibody drug discovery.
  • Proficiency in Microsoft Office (Word, Excel and PowerPoint) and Graphpad Prism.
  • Experience and /or knowledge desired by not required for this position:
    • Antibody screening with ELISA, ELISA and/or cell-based assays
    • Experience with stable cell line generation, FACS sorting and/or experimental design of cell-based assays
  • Local candidate preferred. No relocation assistance offered for this position.

About AlivaMab Discovery Services

AlivaMab Discovery Services (ADS) sets its partners’ antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, ADS delivers drug-quality, fully human antibodies on exceptional timelines. ADS achieves its partners’ design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. ADS focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The ADS team’s experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab® Mouse platforms, ensure the highest probability of success.

 

AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.

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