Deerfield Management Companies

Senior Scientist, Antibody Engineering

Job Locations US-CA-San Diego
Job Post Information* : Posted Date 1 month ago(5/11/2023 12:15 PM)
# of Openings


AlivaMab Discovery Services is seeking an outstanding individual with a wide range of skills in antibody bacteriophage display, and molecular and cellular biology technologies to join our collaborative and innovative therapeutic antibody engineering team.


The annualized anticipated base annual salary for this Senior Scientist position ranges from $136K to $171K. Additionally, this position offers an annual bonus, equity, and other benefits.


Other benefits offered include a 401K retirement savings plan, paid time off (vacation/personal days, holidays, and sick time), long- and short-term disability, health benefits (medical, prescription drug, dental and vision insurance), gym access, and more.


Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to: location, skill level, years and depth of relevant experience, and education.


AlivaMab Discovery Services is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab® Mouse suite of transgenic mice. We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics, and developability, with expanding capabilities for engineering advanced modalities, including multispecifics and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.


  • Design, construct, and implement next-generation antibody display libraries for antibody discovery, engineering, and optimization.
  • Conduct antibody phage display, molecular biology, and analytical data generation and analysis.
  • Design and optimize molecular biology workflows for speed and efficiency.
  • Build and work with state-of-the-art engineered antibodies and multispecifics.
  • Design and tune antibody phage display platform technologies.
  • Execute projects and prepare written reports.
  • Experimental design, experiment execution, and troubleshooting.
  • Work closely with other team members and leaders.
  • Effectively present and communicate concepts and results, both orally and in writing, to colleagues and management.


Key Skills and Requirements:

  • MS with a minimum of 5 years of related experience or PhD with a minimum of 2 years of related experience.
  • Strong knowledge and skills in antibody bacteriophage display and library design/construction.
  • Strong knowledge and skills in molecular biology and construct design.
  • Experience with molecular biology techniques (PCR, DNA/RNA isolation, plasmid prep, gel extraction, cloning, Gibson assembly, Sanger sequence analysis, NGS sequence analysis).
  • Excellent troubleshooting and problem-solving capabilities.
  • Extraordinary attention to detail, planning skills, and organizational skills.
  • History of timeline-driven delivery.
  • Outstanding oral and written communication skills.
  • Independent and creative researcher who demonstrates initiative.
  • Proficiency with Microsoft Office and sequence analysis software.
  • Experience with any of the following is a plus: protein expression in CHO, bacteria, yeast or insect cell systems, antibody engineering and reformatting, high-throughput recombinant expression.

About AlivaMab Discovery Services

AlivaMab Discovery Services (ADS) sets its partners’ antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, ADS delivers drug-quality, fully human antibodies on exceptional timelines. ADS achieves its partners’ design goals for antibody drug discovery and engineering, from simple to extraordinarily challenging, rapidly and efficiently through the generation and fit-for-purpose screening of large, molecularly diverse panels of antibodies, characterized for function, kinetics and developability, and engineering for advanced modalities, including multispecifics and CARs. The ADS team’s experience in antibody drug discovery and development comes from many of the world’s top 15 pharmaceutical companies, including AbbVie, AstraZeneca, Bristol Myers Squibb, Novartis, Pfizer, and Roche/Genentech, and translates across more than 500 discovery programs and 35 clinical candidates. This experience, combined with the use of trusted, proven technologies, including Ablexis’ AlivaMab® Mouse platforms, ensures the highest probability of success.


AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.


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