Deerfield Management Companies

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Job Locations US-CA-San Diego
Job Post Information* : Posted Date 1 month ago(10/29/2021 9:06 AM)
AlivaMab Discovery Services, LLC is seeking a passionate, science-driven individual to join our leadership team and make impactful contributions toward discovering the next generation of antibody-based therapeutics. This position entails extensive external- and internal-facing responsibilities. The Associate Director, Antibody Discovery will present to and interact directly and collaboratively with current and prospective partners of ADS, ranging from top pharmaceutical companies to public and private biotechnology companies. Job functions include creating workplans for therapeutic antibody discovery projects, reporting on progress and problem-solving. The successful candidate will oversee execution of our partners' therapeutic discovery projects by managing immunizations, functional assay development and high-throughput antibody screening to rapidly identify lead candidates. The Associate Director, Antibody Discovery, will collaborate with other functions including project management and operational groups to capture key performance indicators and to improve operational efficiencies. Candidates should be a motivated team players, able to handle multiple projects while working in an exciting, fast-paced environment, to discover the next generation of breakthrough antibody drugs AlivaMab Discovery Services is a rapidly growing leader in the discovery of human antibody therapeutics, trusted by top-tier pharmaceutical and biotechnology companies to deliver panels of drug-quality human antibodies. We deliver on our partners' design goals, from simple to extraordinarily challenging, through collaborative access to our scientists' creativity and experience combined with proven technologies, including the AlivaMab® Mouse suite of transgenic mice. We excel in the rapid and efficient delivery of molecularly diverse therapeutic antibody candidates, well-characterized for function, kinetics and developability, with expanding capabilities for engineering for alternative formats, including multi-specifics and CARs. Our organization is dedicated to creating a healthier world through partnerships that bring better medicines to patients faster, and we recognize our success starts with hiring people who share our passion for science.
ID
2021-1613
Responsibilities
Responsibilities | | The Associate Director, Antibody Discovery will design, lead and execute therapeutic antibody discovery projects. Functional responsibilities include leading an antibody drug discovery team using Ablexis’ AlivaMab Mouse suite of transgenic mice, our suite of immunization-based technologies, high-throughput function-first screens and rapid subsequent screens to identify the best lead candidates. The successful candidate will also apply creative concepts as appropriate to continuously improve and expand functional area capabilities and efficiencies. The Associate Director, Antibody Discovery will also keep current with industry trends and innovations, applying critical thinking in the science and business of therapeutic antibody discovery and development. |   | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. |  
Qualifications
Key Skills and Requirements: | | | - Experienced and creative scientific leadership in therapeutic antibody discovery and highly skilled in the creation and execution of therapeutic discovery workflows, preferably using transgenic mice, including immunization strategies, state-of-the-art hybridoma generation and high-throughput function-first screens. | - Provision of scientific leadership, technical guidance and career development, to direct reports and to discovery teams executing disparate projects running at different phases, to achieve project deliverables on time and within budget. | - Track record of innovation in antibody drug discovery processes and workflows, including familiarity with strengths and weakness of various antibody drug discovery platforms and processes. | - Experience with assay development, stable cell line generation/cell sorting, and general cell biology. | - Outstanding oral and written communication skills. | - Ability to prepare, present and discuss project reports in internal and partner-facing meetings with clarity, accuracy and precision. | - Proficiency in Microsoft Office Suite (Word, Excel and PowerPoint) and GraphPad Prism. | - PhD with at least 6 years of relevant industry experience. | About AlivaMab Discovery Services |   | AlivaMab Discovery Services (ADS) sets its partners’ antibody discovery programs on the fastest and most de-risked path through discovery and development. Trusted by top-tier pharmaceutical and biotechnology companies, ADS delivers drug-quality, fully human antibodies on exceptional timelines. ADS achieves its partners’ design goals, from simple to extraordinarily challenging, through the generation and function-first screening of large, molecularly diverse panels of antibodies. ADS focuses on rapid and efficient delivery of antibodies, characterized for function, kinetics and developability, and engineering for alternative formats, including multi-specifics and CARs. The ADS team’s experience and passion for antibody drug discovery and development combined with the use of trusted, proven technologies, including Ablexis' AlivaMab® Mouse platforms, ensure the highest probability of success. | PM18 | #LI-DNI
Job Locations US-CA-San Diego
Job Post Information* : Posted Date 2 months ago(10/5/2021 8:14 AM)
AlivaMab Discovery Services (ADS) is recruiting for an outstanding individual with skill and experience in mammalian cell culture with strong attention to detail and established ability to multi-task in a dynamic and highly productive environment to join our collaborative and innovative therapeutic antibody discovery team.  Additional knowledge and experience in lab operations is a plus. Title is commensurate with experience and will report to the Manager, Discovery Operations.Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services is expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients.
ID
2021-1601
Responsibilities
Responsibilities | | Your primary responsibilities will be in mammalian cell culture maintenance and handling for hybridoma process, cellular assays, and lab supplies stock maintenance. You will be executing and delivering in support of several projects running concurrently.  We are looking for independent and creative researchers that demonstrate initiative, experiment execution and organization of tasks.  You will work closely with other team members and leaders and success will require effective communication between everyone.
Qualifications
Qualifications | | Key Skills and Requirements | - BS/MS with a minimum of 1 year of related experience | - Strong knowledge and skill in proper handling and maintenance of mammalian cells in culture | - Experience with ELISA and related multi-well plate assays | - Experience with buffer and reagent formulation, serial and limiting dilution pipetting | - Excellent multi-tasking, trouble shooting and problem-solving talent | - Extraordinary attention to detail, planning, and organizational skills | - History of timeline-driven delivery | - Outstanding oral and written communication skills | - Proficiency with Microsoft Office suite applications | Additionally, experience with any of these skills is a plus: animal welfare and handling in a vivarium setting and/or prior success operating in a Lean lab environment. |   | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. |   | PM18 | #LI-DNI |  
Job Locations US-CA-San Diego
Job Post Information* : Posted Date 3 months ago(8/19/2021 12:53 PM)
AlivaMab Discovery Services, LLC (ADS) is recruiting for an outstanding individual with a range of skills to support the successful discovery of fully human antibody drug candidates from the AlivaMab® Mouse platform.  This candidate should be a highly motivated team player, able to multitask in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs. Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services continues expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients. 
ID
2021-1549
Responsibilities
Your primary responsibilities will involve tissue culture and antibody screening utilizing ELISA, Flow Cytometry, and cell-based functional assays.  You will be executing and delivering for projects and preparing written reports.  We are looking for independent and creative researchers that demonstrate initiative, who are capable of experimental design and execution, including troubleshooting.  You will work closely with other team members and leaders.  You will be able to effectively present and communicate concepts and results, both orally and in writing, to the team. 
Qualifications
  | Key Skills and Requirements: | - B.S., M.S., or PhD degree in life sciences or related discipline with three or more years' directly relevant experience | - Demonstrated technical expertise in tissue culture, multi-color flow cytometry and ELISA | - Ability to efficiently work in team-based environment on challenging drug discovery projects utilizing high throughput cell culture and screening techniques | - Experience performing cell-based assays to identify functional antibody candidates and/or experience using Octet system to determine antibody/protein kinetics and affinity is desirable | - Self-motivated with excellent problem-solving, organizational and communication skills with the ability to multitask | - Proficiency in Microsoft Office Suite (Word, Excel and PowerPoint) and Graphpad Prism | - Nice to have: experience in stable cell line generation, FACS sorting, experimental design of cell-based assays | | | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. | | PM18 | #LI-DNI
Job Locations US-CA-San Diego
Job Post Information* : Posted Date 4 months ago(7/22/2021 1:51 PM)
AlivaMab Discovery Services, LLC (ADS) is recruiting for an outstanding Scientist with a strong background in cell biology and experience developing cell-based assays to support the successful discovery of fully human antibody drug candidates from the AlivaMab® Mouse platform.  This candidate should be a highly motivated team player, able to multitask in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs. Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services continues expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients.
ID
2021-1534
Responsibilities
Your primary responsibilities will involve the development of cell-based functional assays for antibody screening utilizing ELISA, Flow Cytometry and Octet-based systems.  You will be executing and delivering for projects and preparing written reports.  We are looking for independent and creative researchers that demonstrate initiative, who are capable of experimental design and execution, including troubleshooting.  You will work closely with other team members and leaders.  You will be able to effectively present and communicate concepts and results, both orally and in writing, to management and clients. 
Qualifications
Key Skills and Requirements: | - PhD in life sciences or related discipline or B.S., M.S. with three or more years' directly relevant experience | - Experience in the design and development of cell-based assays to identify functional antibody candidates | - Demonstrated technical expertise in tissue culture and multi-color flow cytometry, ELISA | - Ability to efficiently work in team-based environment on challenging drug discovery projects utilizing high throughput cell culture and screening techniques | - Experience using Octet system to determine antibody/protein kinetics and affinity is desirable | - Self-motivated with excellent problem-solving, organizational and communication skills with the ability to multitask | - Proficiency in Microsoft Office Suite (Word, Excel and PowerPoint) and Graphpad Prism | - Nice to have: previous experience in stable cell line generation, FACS sorting, protein purification/characterization and general molecular biology skills | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. | | PM18 | #LI-DNI |  
Job Locations US-CA-San Diego
Job Post Information* : Posted Date 3 months ago(8/19/2021 12:38 PM)
AlivaMab Discovery Services, LLC (ADS) is recruiting for an outstanding individual with a range of skill sets supporting the successful discovery of fully human antibody drug candidates from the AlivaMab® Mouse platform.  This candidate should be a motivated team player, able to wear multiple hats while working in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs. Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services continues expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients.
ID
2020-1358
Responsibilities
Responsibilities | | | Your primary responsibilities will be in the area of animal immunizations, hybridoma generation, tissue culture, and antibody screening by ELISA, FACS, and functional assays.  You will be executing and delivering for projects and preparing written reports.  We are looking for independent and creative researchers that demonstrate initiative, who are capable of experimental design and execution, including troubleshooting.  You will work closely with other team members and leaders.  You will be able to effectively present and communicate concepts and results, both orally and in writing, to management and clients. |   |   | |  
Qualifications
  | Key Skills and Requirements: | | | - B.S., M.S., or PhD degree in life sciences or related discipline with three or more years' directly relevant experience | - Impeccable cell culture and sterile technique is essential for success in this role | - Ability to efficiently work in team-based environment on challenging drug discovery projects requiring high throughput cell culture and screening | - Experience in multiple antibody screening assay methods (ELISA, FACS, Octet, functional assays) | - Experience performing cell-based functional assays to identify functional antibody candidates. Functional assay development/optimization experience a plus | - Prior experience in small animal immunizations with recombinant proteins, cells and DNA (HDTVI experience strongly desired) for the discovery of therapeutic antibody drug candidates | - Excellent organization in day to day experiments and timely updating of experiment files | - Proficiency in Microsoft Office Suite (Word, Excel and PowerPoint) and Graphpad Prism | - Nice to have: previous experience in stable cell line generation, hybridoma fusions, FACS sorting, protein purification/characterization and general molecular biology skills | | | | |   | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. | | PM18 | #LI-DNI |