Deerfield Management Companies

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Job Locations US-CA-San Diego
Job Post Information* : Posted Date 3 weeks ago(4/16/2021 5:16 PM)
 AlivaMab Discovery Services (ADS) is recruiting for an outstanding individual with a range of skill sets in antibody analytics to join our collaborative and innovative therapeutic antibody discovery team.  Additional knowledge in antibody production and purification is a plus.  Title will be commensurate with experience. Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services is expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients.
ID
2021-1457
Responsibilities
  | Responsibilities | | Your primary responsibilities will be in the area of antibody purification and analytics.  Candidate will be working with cutting-edge engineered antibody and multispecific platforms. You will be executing and delivering for projects and preparing written reports.  We are looking for independent and creative researchers that demonstrate initiative, who are capable of experimental design, experiment execution and troubleshooting.  You will work closely with other team members and leaders.  You will be able to effectively present and communicate concepts and results, both orally and in writing, to colleagues and management.
Qualifications
  | Qualifications | | Key Skills and Requirements: | - BS/MS with a minimum of 3-5 years of related experience. Higher level of experience considered for the ideal candidate. | - Strong knowledge and skill in antibody protein purification, specifically protein A-based methods | - Experience with HPLC analysis of proteins including SEC, AEX/CEX, and HIC | - Experience with SDS-PAGE and/or SDS-CGE for antibody analysis | - Experience preparing samples and sensors for biosensor applications (eg BLI). Experience with SPR/Biacore is a plus. | - Ability to multi-task | - Excellent trouble shooting and problem-solving capabilities | - Extraordinary attention to detail, planning, and organizational skills | - History of timeline-driven delivery | - Outstanding oral and written communication skills | - Proficiency with Microsoft Office and instrument specific software (Agilent Open Lab, GE Unicorn) | Additionally, experience with any of these skills is a plus: developing methods to determine protein-protein interaction using Biacore/SPR. Experience with Biacore acquisition and evaluation software. Antibody engineering and reformatting, high-throughput recombinant expression, NGS, therapeutic antibody developability assessments, and experience in performing and optimizing transient transfections of antibodies utilizing CHO based suspension systems. |   | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. |   | PM18 | #LI-DNI
Job Locations US-CA-San Diego
Job Post Information* : Posted Date 3 weeks ago(4/16/2021 5:16 PM)
AlivaMab Discovery Services (ADS) is recruiting for an outstanding individual with a range of skill sets in molecular biology and recombinant protein expression to join our collaborative and innovative therapeutic antibody discovery team.  Additional knowledge in antibody engineering, purification, analytics and display systems is a plus.  Title will be commensurate with experience. Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services is expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients.
ID
2021-1456
Responsibilities
Responsibilities | | Your primary responsibilities will be in the area of antibody purification and analytics (antibody purification based on protein A and ion exchange and antibody characterization via SDS-PAGE and SEC-HPLC).  Further responsibilities will include transient expression of antibodies using CHO based expression systems.  The candidate will also be required to assist with molecular biology workflows.  You will be executing and delivering for projects and preparing written reports.  We are looking for independent and creative researchers that demonstrate initiative, who are capable of experimental design, experiment execution and troubleshooting.  You will work closely with other team members and leaders.  You will be able to effectively present and communicate concepts and results, both orally and in writing, to colleagues and management. |  
Qualifications
Qualifications | | Key Skills and Requirements: | | | - BS/MS with a minimum of 3-5 years of related experience | - Strong knowledge and skill in molecular biology and production of recombinant proteins in mammalian culture | - Experience with molecular biology techniques (PCR, DNA/RNA isolation, plasmid prep, gel extraction, cloning, Gibson assembly, Sanger sequence analysis) | - Experience in performing and optimizing transient transfections of antibodies utilizing CHO based suspension systems | - Excellent trouble shooting and problem-solving capabilities | - Extraordinary attention to detail, planning, and organizational skills | - History of timeline-driven delivery | - Outstanding oral and written communication skills | - Proficiency with Microsoft Office and instrument specific software (Agilent Open Lab, GE Unicorn) | Additionally, experience with any of these skills is a plus: expression in bacteria, yeast, or insect cell systems, antibody engineering and reformatting, high-throughput recombinant expression, NGS, therapeutic antibody developability assessments, and protein purification and analysis. |   | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. | PM18 | #LI-DNI |  
Job Locations US-CA-San Diego
Job Post Information* : Posted Date 4 months ago(1/7/2021 11:02 AM)
AlivaMab Discovery Services, LLC (ADS) is recruiting for an outstanding individual with a range of skill sets supporting the successful discovery of fully human antibody drug candidates from the AlivaMab® Mouse platform.  This candidate should be a motivated team player, able to wear multiple hats while working in an exciting, fast-paced environment, working to discover the next generation of breakthrough antibody drugs. Led by personnel with combined decades of experience in therapeutic antibody drug discovery and development, AlivaMab Discovery Services continues expanding its services in therapeutic antibody drug discovery in support of the biotech and pharma communities. You will be a key contributor in a team dedicated to delivering best-in-class therapeutic antibody candidates that will improve outcomes for patients.
ID
2020-1358
Responsibilities
Responsibilities | | | Your primary responsibilities will be in the area of animal immunizations, hybridoma generation, tissue culture, and antibody screening by ELISA, FACS, and functional assays.  You will be executing and delivering for projects and preparing written reports.  We are looking for independent and creative researchers that demonstrate initiative, who are capable of experimental design and execution, including troubleshooting.  You will work closely with other team members and leaders.  You will be able to effectively present and communicate concepts and results, both orally and in writing, to management and clients. |   |   | |  
Qualifications
  | Key Skills and Requirements: | | | - B.S., M.S., or PhD degree in life sciences or related discipline with three or more years' directly relevant experience | - Impeccable cell culture and sterile technique is essential for success in this role | - Ability to efficiently work in team-based environment on challenging drug discovery projects requiring high throughput cell culture and screening | - Experience in multiple antibody screening assay methods (ELISA, FACS, Octet, functional assays) | - Experience performing cell-based functional assays to identify functional antibody candidates. Functional assay development/optimization experience a plus | - Prior experience in small animal immunizations with recombinant proteins, cells and DNA (HDTVI experience strongly desired) for the discovery of therapeutic antibody drug candidates | - Excellent organization in day to day experiments and timely updating of experiment files | - Proficiency in Microsoft Office Suite (Word, Excel and PowerPoint) and Graphpad Prism | - Nice to have: previous experience in stable cell line generation, hybridoma fusions, FACS sorting, protein purification/characterization and general molecular biology skills | | | | |   | AlivaMab Discovery Services provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, gender identification, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law. | | PM18 | #LI-DNI |  

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